Thyrotropin-Secreting Pituitary Tumors*
نویسندگان
چکیده
منابع مشابه
2013 European thyroid association guidelines for the diagnosis and treatment of thyrotropin-secreting pituitary tumors.
Hyperthyroidism is mainly due to autoimmune thyroid disorders or toxic goiter, and very rarely to the presence of thyrotropin (TSH)-secreting pituitary adenomas (TSHomas). These tumors are characterized by high levels of circulating free thyroid hormones (FT4 and FT3) in the presence of nonsuppressed serum TSH concentrations. Failure to correctly diagnose TSHomas may result in inappropriate thy...
متن کاملGuidelines for the Diagnosis and Treatment of Thyrotropin-Secreting Pituitary Tumors
Hyperthyroidism is mainly due to autoimmune thyroid disorders or toxic goiter, and very rarely to the presence of thyrotropin (TSH)-secreting pituitary adenomas (TSHomas). These tumors are characterized by high levels of circulating free thyroid hormones (FT4 and FT3) in the presence of nonsuppressed serum TSH concentrations. Failure to correctly diagnose TSHomas may result in inappropriate thy...
متن کاملThe Intracellular Localization of Hormonal Activity in Transplantable Thyrotropin-Secreting Pituitary Tumors in Mice
Mouse pituitary tumors secreting almost exclusively thyroid stimulating hormone have been characterized electron microscopically. Tumors of known thyrotropin content were separated into nuclear, mitochondrial, microsomal, and soluble fractions by differential centrifugation. The hormonal activity of these fractions was correlated with that of the total homogenates and with their nitrogen and ph...
متن کاملThyrotropin secreting pituitary adenoma accompanying a silent somatotropinoma.
Thyroid stimulating hormone (TSH) secreting pituitary adenomas are rare tumors manifested as hyperthyroidism with goiter in the presence of elevated TSH. We present a case with pituitary adenoma secreting both TSH and growth hormone (GH) with the prominent clinical findings of hyperthyroidism but without clinical findings of acromegaly. Pituitary magnetic resonance imaging revealed a macroadeno...
متن کاملA Case of Thyrotropin-Secreting Pituitary Adenoma (TSH-oma)
Thyrotropin-secreting pituitary adenomas (TSHomas) are rare tumors and represent about 1-2% of all pituitary adenomas (prevalence is about one case per million) and cause secondary or central hyperthyroidism. The number of reported cases of TSH-omas tripled in the last decade. The increased number of reported cases resulted principally from the introduction of ultrasensitive immunometric assay ...
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ژورنال
عنوان ژورنال: Endocrine Reviews
سال: 1996
ISSN: 0163-769X,1945-7189
DOI: 10.1210/edrv-17-6-610